A Handbook Of Gene And Cell Therapy

A Handbook of Gene and Cell Therapy PDF
Author: Clévio Nóbrega
Publisher: Springer Nature
ISBN: 3030413330
Size: 47.88 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 188
View: 1264

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Book Description: This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of RNA interference, the completion of the Human Genome project or the development of induced pluripotent stem cells (iPSc) and the basics of gene therapy are covered. This is a great book for students, teachers, biomedical researchers delving into gene/cell therapy or researchers borrowing skills from this scientific field.

Handbook Of Cardiac Stem Cell Therapy

Handbook of Cardiac Stem Cell Therapy PDF
Author: Ioannis Dimarakis
Publisher: World Scientific
ISBN: 1848162561
Size: 22.33 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 285
View: 3307

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Book Description: This book is an impressive compilation of contributions on the hot topic of cardiac stem cell therapy from leading groups all over the world. In the assembly of chapters, a structured approach is adopted; starting from the clinician's perspective, all developments in both the experimental and clinical research areas are covered. This journey will take the reader from the bench-top to the bedside, with all chapters written by leading authorities in their respective fields, including data still in press with medical journals. So, beyond being excellent as an overall update for scientists in the field of cardiac stem cell therapy, this book will likely prove an indispensable tool for every budding scientist considering a research project within this field.

Handbook Of Traumatic Brain Injury And Neurodegeneration

Handbook of Traumatic Brain Injury and Neurodegeneration PDF
Author: R.J. Castellani
Publisher: IOS Press
ISBN: 164368065X
Size: 46.56 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 504
View: 623

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Book Description: Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.

Handbook Of Pharmaceutical Biotechnology

Handbook of Pharmaceutical Biotechnology PDF
Author: Shayne Cox Gad
Publisher: John Wiley & Sons
ISBN: 9780470117101
Size: 43.29 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 1680
View: 1403

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Book Description: A practical overview of a full rangeof approaches to discovering, selecting, and producing biotechnology-derived drugs The Handbook of Pharmaceutical Biotechnology helps pharmaceutical scientists develop biotech drugs through a comprehensive framework that spans the process from discovery, development, and manufacturing through validation and registration. With chapters written by leading practitioners in their specialty areas, this reference: Provides an overview of biotechnology used in the drug development process Covers extensive applications, plus regulations and validation methods Features fifty chapters covering all the major approaches to the challenge of identifying, producing, and formulating new biologically derived therapeutics With its unparalleled breadth of topics and approaches, this handbook is a core reference for pharmaceutical scientists, including development researchers, toxicologists, biochemists, molecular biologists, cell biologists, immunologists, and formulation chemists. It is also a great resource for quality assurance/assessment/control managers, biotechnology technicians, and others in the biotech industry.

Handbook Of Clinical Neurology

Handbook of Clinical Neurology PDF
Author: P. J. Vinken
Publisher:
ISBN:
Size: 47.38 MB
Format: PDF, ePub, Docs
Category : Lipidoses
Languages : en
Pages : 772
View: 2818

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Book Description:

Human Gene Therapy

Human Gene Therapy PDF
Author:
Publisher:
ISBN:
Size: 33.17 MB
Format: PDF
Category : Gene therapy
Languages : en
Pages :
View: 6395

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Book Description:

Handbook Of Stem Cells

Handbook of Stem Cells PDF
Author: Anthony Atala
Publisher: Academic Press
ISBN: 0123859433
Size: 25.81 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 1074
View: 5903

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Book Description: New discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells and Cell Biology and Adult and Fetal Stem Cells, this work contains contributions from the world’s experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system. Provides comprehensive coverage on this highly topical subject Contains contributions by the foremost authorities and premiere names in the field of stem cell research Companion website - http://booksite.elsevier.com/9780123859426/ - contains over 250 color figures in presentation format

Handbook Of Biomineralization

Handbook of Biomineralization PDF
Author: Edmund Bäuerlein
Publisher: Wiley-VCH
ISBN:
Size: 47.81 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 424
View: 7146

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Book Description: This first comprehensive overview of the modern aspects of biomineralization represents life and materials science at its best: Bioinspired pathways are the hot topics in many disciplines and this holds especially true for biomineralization. Here, the editors - well-known members of associations and prestigious institutes - have assembled an international team of renowned authors to provide first-hand research results. This third volume deals with biomineralization in medicine, paying closer attention to bones, teeth and pathological calcifications. An interdisciplinary must-have account, for biochemists, bioinorganic chemists, lecturers in chemistry and biochemistry, materials scientists, biologists, and solid state physicists.

A Handbook Of Mouse Models Of Cardiovascular Disease

A Handbook of Mouse Models of Cardiovascular Disease PDF
Author: Qingbo Xu
Publisher: John Wiley & Sons
ISBN: 0470028785
Size: 31.82 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 402
View: 2443

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Book Description: The availability of well-defined genetic strains and the ability to create transgenic and knockout mice makes mouse models extremely valuable biomedical tools. Their suitability as an experimental system for cardiovascular research depends on the individual investigator’s ability to manipulate the mice surgically. Many mouse models require microsurgical techniques, which hitherto could not be performed without practical training. This comprehensive handbook enables scientists to develop these models in their own laboratories. A Handbook of Mouse Models of Cardiovascular Disease is the first book to address pathology in mouse models of heart disease, providing the reader with essential information on technical assays in artificially created models. It includes background information on individual cardiovascular diseases, describes detailed methods and materials used for establishing each mouse model, discusses the problems that may appear in the experiments, and provides examples of applications of the model. A Handbook of Mouse Models of Cardiovascular Disease: Describes mouse models of all important cardiovascular diseases, including atherosclerosis, atrial fibrillation and thrombosis Features videos of key experimental procedures on the accompanying CD, allowing researchers to learn the techniques by directly watching the whole operational procedure Describes how to establish each experimental model with detailed protocols and tips on dealing with common operational problems Highlights potential applications of each model in areas such as pathogenesis, gene transfer, therapy and pathophysiology This handbook is an invaluable resource for researchers in cardiovascular disease, pathology, physiology, interested in the mechanism of vascular disorders and therapeutic approaches. It is also relevant to clinicians seeking to understand the pathology of cardiovascular disease and the rationale for interventions, and of interest to the pharmaceutical industry and all those involved in drug discovery/development for cardiovascular disease.

Handbook Of Process Chromatography

Handbook of Process Chromatography PDF
Author: Gail K. Sofer
Publisher: Academic Press
ISBN:
Size: 55.21 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 387
View: 5445

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Book Description: With examples from companies with establised processes and approved biotherapeutics, this pack considers the entire scope of process chromatography, including scale-up, regulatory issues, equipment, evaluation studies, scheduling and cost effectiveness.